The Rhodope metallogenic province in Bulgaria includes the Rhodopes, Rila, Pirin and SW Bulgaria, Osogovo. The metallogenic appearance of this province was formed during the late Alpine era, when almost all industrial accumulations of metallic and non-metallic minerals were formed. The Rhodope metallogenic province during the Paleogene is an arena of post-collision extension. Metamorphic processes and manifestations of asbestos, talc, magnesite, kyanite and graphite are associated with the processes of metamorphism. Hydrothermal and skarn deposits, as well as pegmatoid deposits and manifestations of muscovite, feldspar and jewelry quartz, associate W, Mo, U, Fe, Pb-Zn, Au and fluorite with the early extension granitoid plutons. Hydrothermal and skarn Pb-Zn, hydrothermal Au, Au-Pb-Zn, Sb, U, fluorite, alunite, bentonite, zeolites, as well as magmatic perlite and other deposits and manifestations are associated with late extension magmatism.