Our era is marked by a steady rise in the incidence of solid tumors, as well as by a molecular biological and technological “boom” in fundamental and clinical oncology. Modern treatment is no longer merely “organ-preserving,” but also personalized, based on a comprehensive multidisciplinary approach. Practicing surgeons need a thorough understanding of cancer as a biological process. This volume is an attempt to address this need. It systematically covers tumor biology, epidemiology, and cancer control, the fundamental principles and methods of diagnosis and treatment, as well as their integration over time. It also addresses some important legal and ethical issues. The authors are leading specialists in their respective fields. Volume XIX is suitable for physicians specializing in surgery and other surgical specialties, residents in medical oncology, and students.